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St. Louis to San Diego flight ticket price

Compare live prices for STL to SAN. Use the search panel to change origin, destination, passengers, cabin and trip type instantly.
STL → SAN Approx. 2501.17 km 08 May 2026 Live inventory
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Showing 25 of 111 live flights
Delta Air Lines
DL-2421
19:59
05/08/2026
STL
St Louis Lambert International Airport
3h 44m
1 Stop
⏱ SLC · 0h 31mSLC Airport
23:43
05/08/2026
SAN
San Diego International Airport
₹13,720
per person
✕ Non-refundable2 fare options
Delta Air Lines
DL-2363
07:00
05/08/2026
STL
St Louis Lambert International Airport
5h 17m
1 Stop
⏱ SLC · 2h 9mSLC Airport
12:17
05/08/2026
SAN
San Diego International Airport
₹13,720
per person
✕ Non-refundable2 fare options
Delta Air Lines
DL-1597
06:21
05/08/2026
STL
St Louis Lambert International Airport
4h 16m
1 Stop
⏱ MSP · 0h 51mMSP Airport
10:37
05/08/2026
SAN
San Diego International Airport
₹13,720
per person
✕ Non-refundable2 fare options
Delta Air Lines
DL-1605
17:36
05/08/2026
STL
St Louis Lambert International Airport
6h 5m
1 Stop
⏱ MSP · 2h 42mMSP Airport
23:41
05/08/2026
SAN
San Diego International Airport
₹13,720
per person
✕ Non-refundable2 fare options
American Airlines
AA-2261
05:20
05/08/2026
STL
St Louis Lambert International Airport
4h 49m
1 Stop
⏱ DFW · 1h 31mDFW Airport
10:09
05/08/2026
SAN
San Diego International Airport
₹13,720
per person
✕ Non-refundable14 fare options
American Airlines
AA-2444
07:05
05/08/2026
STL
St Louis Lambert International Airport
5h 23m
1 Stop
⏱ ORD · 1h 19mORD Airport
12:28
05/08/2026
SAN
San Diego International Airport
₹13,720
per person
✕ Non-refundable14 fare options
American Airlines
AA-4135
08:54
05/08/2026
STL
St Louis Lambert International Airport
5h 24m
1 Stop
⏱ ORD · 1h 23mORD Airport
14:18
05/08/2026
SAN
San Diego International Airport
₹13,720
per person
✕ Non-refundable14 fare options
Delta Air Lines
DL-2455
14:27
05/08/2026
STL
St Louis Lambert International Airport
4h 18m
1 Stop
⏱ SLC · 1h 5mSLC Airport
18:45
05/08/2026
SAN
San Diego International Airport
₹13,720
per person
✕ Non-refundable
Delta Air Lines
DL-5325
08:53
05/08/2026
STL
St Louis Lambert International Airport
4h 24m
1 Stop
⏱ MSP · 0h 55mMSP Airport
13:17
05/08/2026
SAN
San Diego International Airport
₹13,720
per person
✕ Non-refundable
American Airlines
AA-418
17:21
05/08/2026
STL
St Louis Lambert International Airport
6h 12m
1 Stop
⏱ ORD · 2h 5mORD Airport
23:33
05/08/2026
SAN
San Diego International Airport
₹13,720
per person
✕ Non-refundable13 fare options
American Airlines
AA-858
07:00
05/08/2026
STL
St Louis Lambert International Airport
6h 14m
1 Stop
⏱ CLT · 0h 59mCLT Airport
13:14
05/08/2026
SAN
San Diego International Airport
₹13,720
per person
✕ Non-refundable13 fare options
American Airlines
AA-3128
05:51
05/08/2026
STL
St Louis Lambert International Airport
6h 37m
1 Stop
⏱ ORD · 2h 34mORD Airport
12:28
05/08/2026
SAN
San Diego International Airport
₹13,720
per person
✕ Non-refundable13 fare options
American Airlines
AA-2958
14:12
05/08/2026
STL
St Louis Lambert International Airport
6h 38m
1 Stop
⏱ CLT · 1h 24mCLT Airport
20:50
05/08/2026
SAN
San Diego International Airport
₹13,720
per person
✕ Non-refundable12 fare options
Delta Air Lines
DL-1597
06:21
05/08/2026
STL
St Louis Lambert International Airport
6h 56m
1 Stop
⏱ MSP · 3h 26mMSP Airport
13:17
05/08/2026
SAN
San Diego International Airport
₹13,720
per person
✕ Non-refundable
American Airlines
AA-2444
07:05
05/08/2026
STL
St Louis Lambert International Airport
7h 13m
1 Stop
⏱ ORD · 3h 9mORD Airport
14:18
05/08/2026
SAN
San Diego International Airport
₹13,720
per person
✕ Non-refundable12 fare options
Southwest Airlines
WN-4459
18:45
05/08/2026
STL
St Louis Lambert International Airport
3h 50m
1 Stop
⏱ DEN · 1h 0mDEN Airport
22:35
05/08/2026
SAN
San Diego International Airport
₹14,215
per person
✕ Non-refundable6 fare options
Southwest Airlines
WN-4481
08:30
05/08/2026
STL
St Louis Lambert International Airport
3h 40m
1 Stop
⏱ MCI · 1h 5mMCI Airport
12:10
05/08/2026
SAN
San Diego International Airport
₹14,215
per person
✕ Non-refundable6 fare options
American Airlines
AA-2945
18:11
05/08/2026
STL
St Louis Lambert International Airport
3h 49m
1 Stop
⏱ DFW · 0h 40mDFW Airport
22:00
05/08/2026
SAN
San Diego International Airport
₹15,660
per person
✕ Non-refundable8 fare options
American Airlines
AA-2945
18:11
05/08/2026
STL
St Louis Lambert International Airport
5h 45m
1 Stop
⏱ DFW · 2h 41mDFW Airport
23:56
05/08/2026
SAN
San Diego International Airport
₹15,660
per person
✕ Non-refundable8 fare options
American Airlines
AA-2261
05:20
05/08/2026
STL
St Louis Lambert International Airport
6h 54m
1 Stop
⏱ DFW · 3h 39mDFW Airport
12:14
05/08/2026
SAN
San Diego International Airport
₹15,660
per person
✕ Non-refundable7 fare options
Southwest Airlines
WN-4472
13:30
05/08/2026
STL
St Louis Lambert International Airport
4h 10m
1 Stop
⏱ LAS · 1h 10mLAS Airport
17:40
05/08/2026
SAN
San Diego International Airport
₹18,046
per person
✕ Non-refundable5 fare options
Southwest Airlines
WN-4472
13:30
05/08/2026
STL
St Louis Lambert International Airport
5h 30m
1 Stop
⏱ LAS · 2h 35mLAS Airport
19:00
05/08/2026
SAN
San Diego International Airport
₹18,046
per person
✕ Non-refundable5 fare options
United Airlines
UA-1770
17:59
05/08/2026
STL
St Louis Lambert International Airport
4h 17m
1 Stop
⏱ DEN · 1h 13mDEN Airport
22:16
05/08/2026
SAN
San Diego International Airport
₹18,348
per person
✕ Non-refundable7 fare options
United Airlines
UA-1371
06:00
05/08/2026
STL
St Louis Lambert International Airport
5h 3m
1 Stop
⏱ IAH · 1h 12mIAH Airport
11:03
05/08/2026
SAN
San Diego International Airport
₹18,348
per person
✕ Non-refundable7 fare options
United Airlines
UA-4423
06:30
05/08/2026
STL
St Louis Lambert International Airport
4h 55m
1 Stop
⏱ ORD · 0h 52mORD Airport
11:25
05/08/2026
SAN
San Diego International Airport
₹18,348
per person
✕ Non-refundable7 fare options
😕 No flights match your filters.
St. Louis (STL)
📍 St Louis Lambert International Airport
🌍 United States
🕐 GMT -6
📐 Latitude: 38.748697
📐 Longitude: -90.370003
San Diego (SAN)
📍 San Diego International Airport
🌍 United States
🕐 GMT -8
📐 Latitude: 32.7336006165
📐 Longitude: -117.190002441

✈ Distance: St. Louis,USA to San Diego,USA2501.17 km

📅 Results on this page are loaded for 08 May 2026. Click View all flights for the complete live search.

St. Louis to San Diego — what to expect when booking

The STL–SAN route is served by multiple carriers throughout the year. Fares on this route can move quickly — a price available now may not be there 30 minutes later.

If your dates are flexible, try shifting your departure by a day or two using the date strip above. Mid-week departures often show lower base fares compared to weekend starts on many routes.

The distance between St. Louis,USA and San Diego,USA is approximately 2501.17 km.

Before you book

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More flights from St. Louis (STL)
54 routes
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St. Louis Fort Leonard Wood
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St. Louis Fort Myers
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St. Louis Fort Worth
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St. Louis Grand Rapids
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St. Louis Houston
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St. Louis Jonesboro
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St. Louis Kirksville
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St. Louis Little Rock
STL → LIT
St. Louis Los Angeles
STL → LAX
St. Louis Marion
STL → MWA
St. Louis Miami
STL → MIA
St. Louis Milwaukee
STL → MKE
St. Louis Minneapolis
STL → MSP
St. Louis Montego Bay
STL → MBJ
St. Louis Nashville
STL → BNA
St. Louis New Orleans
STL → MSY
St. Louis New York
STL → LGA
St. Louis Oklahoma City
STL → OKC
St. Louis Omaha
STL → OMA
St. Louis Orlando
STL → MCO
St. Louis Owensboro
STL → OWB
St. Louis Philadelphia
STL → PHL
St. Louis Phoenix
STL → PHX
St. Louis Pittsburgh International Airport
STL → PIT
St. Louis Puerto Vallarta
STL → PVR
St. Louis Punta Cana
STL → PUJ
St. Louis Quincy
STL → UIN
St. Louis Raleigh
STL → RDU
St. Louis Salt Lake City
STL → SLC
St. Louis San Antonio
STL → SAT
St. Louis San Francisco
STL → SFO
St. Louis Seattle
STL → SEA
St. Louis Tampa
STL → TPA
St. Louis Toronto
STL → YYZ
St. Louis Tulsa
STL → TUL
St. Louis Washington DC
STL → DCA
More flights from San Diego (SAN)
53 routes
San Diego Albuquerque
SAN → ABQ
San Diego Atlanta
SAN → ATL
San Diego Austin
SAN → AUS
San Diego Bellingham
SAN → BLI
San Diego Boise
SAN → BOI
San Diego Boston
SAN → BOS
San Diego Calgary
SAN → YYC
San Diego Charlotte
SAN → CLT
San Diego Chicago
SAN → ORD
San Diego Denver
SAN → DEN
San Diego Detroit
SAN → DTW
San Diego Fort Worth
SAN → DFW
San Diego Fresno
SAN → FAT
San Diego Honolulu
SAN → HNL
San Diego Houston
SAN → IAH
San Diego Houston
SAN → HOU
San Diego Imperial
SAN → IPL
San Diego Kahului
SAN → OGG
San Diego Kansas City
SAN → MCI
San Diego Las Vegas
SAN → LAS
San Diego Lihue
SAN → LIH
San Diego London
SAN → LHR
San Diego Los Angeles
SAN → LAX
San Diego Louisville
SAN → SDF
San Diego Mexico City
SAN → MEX
San Diego Miami
SAN → MIA
San Diego Minneapolis
SAN → MSP
San Diego Monterey
SAN → MRY
San Diego Nashville
SAN → BNA
San Diego New Orleans
SAN → MSY
San Diego New York
SAN → JFK
San Diego Oakland
SAN → OAK
San Diego Omaha
SAN → OMA
San Diego Orlando
SAN → MCO
San Diego Philadelphia
SAN → PHL
San Diego Phoenix
SAN → PHX
San Diego Portland International
SAN → PDX
San Diego Providence
SAN → PVD
San Diego Puerto Vallarta
SAN → PVR
San Diego Reno
SAN → RNO
San Diego Sacramento
SAN → SMF
San Diego Salt Lake City
SAN → SLC
San Diego San Antonio
SAN → SAT
San Diego San Francisco
SAN → SFO
San Diego San Jose Cabo
SAN → SJD
San Diego San Jose
SAN → SJC
San Diego Santa Rosa
SAN → STS
San Diego Seattle
SAN → SEA
San Diego St. Louis
SAN → STL
San Diego Tokyo
SAN → NRT
San Diego Toronto
SAN → YYZ
San Diego Tucson
SAN → TUS
San Diego Washington DC
SAN → BWI
❓ Frequently asked questions — St. Louis to San Diego flights

Generally yes — fares on most routes are most competitive around 4–6 weeks before departure. Booking earlier usually means better availability and a lower base fare when your dates are fixed.

The straight-line distance between St. Louis,USA (STL) and San Diego,USA (SAN) is approximately 2501.17 km. Actual flying distance may vary slightly depending on routing.

Non-stop availability on this route varies by airline schedule and season. Use the filters below to quickly check whether direct options are available on your selected date.

Mid-week departures often show lower prices than weekend travel on many routes. Use the date strip above to compare nearby days quickly.